Dr. Nicola M Grande received his degree in Dentistry (DDS) from the Catholic University of Sacred Heart (UCSC), Rome, Italy in 1999 with a degree thesis on the fracture of NiTi rotary instruments. After two years in the Department of Endodontics at the same University, he served as an Assistant Professor in Endodontics from 2001 to 2009. He has been Professor of Endodontics in the School of Dental Hygiene (2002-2008). From 2009 to 2013 he has worked as researcher in the Department of Endodontics at the University of Roma “La Sapienza”. He completed his PhD program at the Catholic University of Sacred Heart, in 2009, with a thesis on an innovative technique for the restoration of the endodontically treated teeth, that he has invented. Presently he is Professor and Chair of Endodontics at UCSC. His main scientific interests are the preparation of root canals with Nickel-Titanium rotary instruments, the study of anatomy and preparation of endodontic anatomy by micro-computed tomography techniques and the restoration of the endodontically treated teeth with new conservative approaches. He contributed in the development of different instrument systems and new techniques and he is holder of different international patents in the field of dentistry. He is certified member of the European Society of Endodontology (ESE), of the American Association of Endodontics (AAE) and active member of the Italian Society of Conservative Dentistry (SIDOC) and of the Italian Academy of Endodontics (AIE). He has been elected as the forthcoming president of Italian Academy of Endodontics for the years 2023/2024. Dr.Grande is member of the Editorial board for the major internation journals in endodontic field; he has published extensively in international peer-reviewed journals, where he has more than 100 papers published with impact factor, in 2021 his H-index is 44 and he has more than 1500 citations. He lectures since more than 15 years both nationally and internationally. He is working as specialist of endodontics and micro-surgery in his own private clinic in Rome Italy.